■■When not to use the product■■

(If you do not follow these instructions, the current symptoms may worsen or adverse reactions/incidents are more likely to occur.)

1. This product should not be used in the following persons:

Persons who have had an allergic symptom to this drug or its ingredients.

Patients who have experienced asthma from taking this drug or other cold remedies, antipyretic analgesics.

Children under 12 years old.

2. This drug should not be taken together with the following drugs:

Other cold medicines, antipyretics/analgesics, sedatives, expectorants, internal medicine, etc. containing antihistamines (internal medicine for rhinitis, medicine for motion sickness, medicine for allergies, etc.) and gastrointestinal analgesics

●After taking this drug, do not drive a car or operate machinery (sleepiness may occur).

For those who are lactating, do not use this medicine or avoid lactating while using this medicine. Do not drink alcohol before and after taking this drug.

● Do not take this medicine for a long time

■■Consultation■■

●The following persons should contact a physician, pharmacist, or registered salesperson for a consultation before administration.

1. Patients undergoing medical treatment from a physician or dentist.

2. Pregnant women or women suspected of being pregnant.

3. The elderly

4. Patients who have experienced allergic symptoms associated with drugs, etc. Persons with the following symptoms: hyperthermia, urination difficulty

5. Persons diagnosed as having the following: thyroid disease Diabetes, heart disease, hypertension, liver disease, kidney disease, gastric/duodenal ulcer, glaucoma, respiratory functional disorder, obstructive sleep apnea syndrome, adiposity

●If the following symptoms are observed after taking this drug, these may be adverse reactions, so immediately discontinue the use of this drug, and show this document to your physician, pharmacist, or registered salesperson for a consultation.

1. Affected area: Skin

Symptoms: rash/redness, itching

2. Affected area: Gastrointestinal system,

Symptoms: vomitingLoss of appetite

3. Affected area: Neuropsychiatric system

Symptoms: dizziness

4. Affected area: Urinary system

Symptoms: urination difficulty

5. Other: excessive temperature decrease

●The following serious symptoms may occur in rare cases. In such cases, immediately seek medical aid from a physician.

1. Condition: Shock (anaphylaxis)

Symptoms: such as itching of skin, urticaria, hoarseness, sneezing, itchy throat, breathing difficulties, palpitations, and clouding of consciousness may occur immediately after take.

2. Condition: oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis, acute generalised exanthematous pustulosis

Symptoms: Hyperthermia, ocular hyperaemia, eye discharge, lip erosion, pain throat, widespread skin rash/redness, small pimples (small pustules) on reddened skin, general malaise, anorexia, etc. may persist or suddenly worsen.

3. Condition: Hepatic function failure

Symptoms: such as fever, itching, rash, jaundice (yellowing of skin and white of eyes), brown urine, general malaise, loss of appetite, etc. may occur.

In 1 packet (0.96 g)

Guaifenesin 60mg

Dihydrocodeine Phosphate 8mg

dl-Methylephedrine Hydrochloride 20mg

Acetaminophen 300mg

Chlorpheniramine Maleate 2.5mg

Anhydrous caffeine 25mg Riboflavin 4mg

Other ingredients: cellulose,anhydrous silicic acid ,Potato starch,D-Mannitol ,Hydroxypropylcellulose,Magnesium aluminometasilicate ,Aspartame (L- phenylalanine compound),flavor,Vanillin

No need to worry if you have yellow urine after taking the drug because it is caused by the vitamin B2 contained in the drug.

Relief of various symptoms of a common cold: running nose, stuffy nose, sneezing, sore throat, cough, phlegm (sputum), chills (feeling cold due to fever), fever, headache, joint pain, and muscle pain.

Take the following dose with cold or lukewarm water within 30 minutes after a meal whenever possible. 15 years or over: 1 packet per dose, 3 times daily

Children aged 12–14 years old: two-thirds of the pack, 3 times a day

Children under 12 years old: Do not take this drug.

Comply with the prescribed dosage and administration instructions. The use of the drug in children should be supervised by a parent.

■■When not to use the product■■

(If you do not follow these instructions, the current symptoms may worsen or adverse reactions/incidents are more likely to occur.)

1. This product should not be used in the following persons:

Persons who have had an allergic symptom to this drug or its ingredients.

Patients who have experienced asthma from taking this drug or other cold remedies, antipyretic analgesics.

Children under 12 years old.

2. This drug should not be taken together with the following drugs:

Other cold medicines, antipyretics/analgesics, sedatives, expectorants, internal medicine, etc. containing antihistamines (internal medicine for rhinitis, medicine for motion sickness, medicine for allergies, etc.) and gastrointestinal analgesics

●After taking this drug, do not drive a car or operate machinery (sleepiness may occur).

For those who are lactating, do not use this medicine or avoid lactating while using this medicine. Do not drink alcohol before and after taking this drug.

● Do not take this medicine for a long time

■■Consultation■■

●The following persons should contact a physician, pharmacist, or registered salesperson for a consultation before administration.

1. Patients undergoing medical treatment from a physician or dentist.

2. Pregnant women or women suspected of being pregnant.

3. The elderly

4. Patients who have experienced allergic symptoms associated with drugs, etc. Persons with the following symptoms: hyperthermia, urination difficulty

5. Persons diagnosed as having the following: thyroid disease Diabetes, heart disease, hypertension, liver disease, kidney disease, gastric/duodenal ulcer, glaucoma, respiratory functional disorder, obstructive sleep apnea syndrome, adiposity

●If the following symptoms are observed after taking this drug, these may be adverse reactions, so immediately discontinue the use of this drug, and show this document to your physician, pharmacist, or registered salesperson for a consultation.

1. Affected area: Skin

Symptoms: rash/redness, itching

2. Affected area: Gastrointestinal system,

Symptoms: vomitingLoss of appetite

3. Affected area: Neuropsychiatric system

Symptoms: dizziness

4. Affected area: Urinary system

Symptoms: urination difficulty

5. Other: excessive temperature decrease

●The following serious symptoms may occur in rare cases. In such cases, immediately seek medical aid from a physician.

1. Condition: Shock (anaphylaxis)

Symptoms: such as itching of skin, urticaria, hoarseness, sneezing, itchy throat, breathing difficulties, palpitations, and clouding of consciousness may occur immediately after take.

2. Condition: oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis, acute generalised exanthematous pustulosis

Symptoms: Hyperthermia, ocular hyperaemia, eye discharge, lip erosion, pain throat, widespread skin rash/redness, small pimples (small pustules) on reddened skin, general malaise, anorexia, etc. may persist or suddenly worsen.

3. Condition: Hepatic function failure

Symptoms: such as fever, itching, rash, jaundice (yellowing of skin and white of eyes), brown urine, general malaise, loss of appetite, etc. may occur.

Taisho Pharmaceutical Co., Ltd.

3-24-1, Takada, Toyodhima-ku, Tokyo

03-3985-1800

8:30~21:00 (excluding Saturdays, Sundays and holidays)